Dr. Cote is a toxicologist with expertise in environmental risk assessment, and the interface of science and public policy. Her research focuses on causes of cancer and respiratory diseases, and development of risk assessment approaches. She lectures in risk assessment, and public policy. Formerly, she was a senior science advisor, associate laboratory director and division director at the US Environmental Protection Agency, where she was responsible for oversight of EPA health assessments for high priority pollutants, development of science policies and risk assessment methodologies, air pollution research, and effective interface with EPA’s regulatory affairs. She has been on the faculty at Duke University and New York University Medical School, and is an associate at Risk Science International, Ottawa, Canada.
Areas of Expertise
- Air pollution
- environmental chemicals mechanisms of action
- Cancer and respiratory disease
- Risk assessment
- Public policy
Education, Licensure & Certifications
- PhD, Medical Sciences granted jointly by the University of New Mexico & Duke University Medical Centers
- Postdoctoral fellow at Duke University Medical School, Department of Cell Biology
- Postdoctoral fellow New York University Medical School, Department of Environmental Medicine
- Board Certified in Toxicology, 198
Courses
- EHOH 6618 Environmental Health Policy and Practice, lecture on Environmental Law and Public Policy
Research
- Health Canada, International Landscape for Endocrine Disruptors: Jan 2018-Jan 2019, Legislation, Polic, Practices and Scientific Approaches for Priority Setting and Risk Assessment, PI-Lead
- European Union Joint Research Center, Key characteristics of repeat dose systemic toxicants; Oct 2020-Oct 2022; PI
Publications and Presentations
- Hobbie K, Shao K, Henning C, Mendez W, Lee JS, Cote I, Druwe I, Allen Davis JA, Gift JS. Use of study-specific MOE-like estimates to prioritize health effects from chemical exposure for analysis in human health assessments. Environment International, Accepted for publication, 2020
- Mendez W, Kan S, Lee JS, Cote I, Drewe IL, Davis A, Gift JS. Model averaging methods for the evaluation of dose-response model uncertainty when assessing the suitability of studies for estimating risk. Environment International. In press. Volume 143, October 2020
- Krewski D, Andersen M, Tyshenko MG, Krishnan K, Hartung KT, Boekelheide K, Wambaugh J, Jones D, Whelan M, Thomas R, Yauk C, Cote I. Toxicity Testing in the 21st Century: Progress in the Past Decade and Future Perspectives, Arch Toxicol. 2020 Jan;94(1):1-58
- Cote I, Vandenberg JJ, Druwe, IL, Angrish M. “Incorporating Epigenomics into a Risk Assessment Framework”, in Toxico-Epigenetics: Core Principles and Applications. McCullough S., and DC Dolinoy (editors). Elsevier, Amsterdam, 2019, pp. 289-310, ISBN 9780128124338
- Cote IL, McCullough SD, Hines RN, Vandenberg JJ. Application of epigenetic data in human health risk assessment. Curr Opin Toxicol. 2017 Nov 6;6:71-78
