Dr. Bauer is an associate professor in Department of Environmental & Occupational Health (EOH) at the Colorado School of Public Health. She is interested in how environmental and occupational exposures to toxicants contribute to human lung diseases, particularly asthma, chronic obstructive pulmonary disease, and cancer. The focus of her research is on determining the molecular mechanisms driving these diseases, and use these mechanistic insights to predict disease incidence, and develop preventive and interventive strategies for improving outcomes in human health. Prior to coming to Colorado, she was a faculty member in the Department of Pathobiology and Center for Integrative Toxicology at Michigan State University. She has a strong background in environmental toxicology, pharmacology, and environmental genetics through training at the University of Colorado Health Sciences (UCHSC), CIIT Centers for Health Research, and the National Institute for Environmental Health Sciences (NIEHS). Her post-doctoral training was at the National Institute for Environmental Health Sciences in the Laboratory of Respiratory Biology with Dr. Steven Kleeberger on environmental genetics. She received her PhD from the University of Colorado in Pharmacology in Dr. Al Malkinson’s laboratory and her B.S. in biochemistry from Pennsylvania State University. She has on-going research studies with numerous collaborators from CU Boulder to Michigan State University to Ruhr-University, Bochum, Germany.
Learn more about Dr. Bauer's Research Lab.
Areas of Expertise
- Environmental and occupational toxicant contribution to lung diseases, such as cancer and asthma
- Air pollution toxicology
- Polycyclic aromatic hydrocarbon (PAH) toxicology
- Bioactive lipids in disease prevention
- Animal models of lung cancer
Education, Licensure & Certifications
- PhD, Pharmacology, University of Colorado Health Sciences Center
- BS, Biochemistry, Pennsylvania State University
Awards
- Paper of the Year, co-author, Particle and Fibre Toxicology, 2022
- Elected member, Alpha Upsilon Chapter of Delta Omega National Honor Society in Public Health, 2018
- American Thoracic Society Fellow, 2018
- Paper of the Year, co-author, Inhalation and Respiratory Specialty Section, Society of Toxicology, 2015
Courses
- EHOH 6616 Environmental and Occupational Toxicology
- EHOH 6643 Air Quality and Public Health
- EHOH 7631 Survey of Environmental & Occupational Health Methods
- EHOH 7632 Advanced Field Methods in Environmental & Occupational Health
Research
- National Institute of Environmental Health Sciences (NIEHS). “High-throughput toxicity screening of environmental contaminants and drug candidates using a novel gap junction intercellular communication bioassay in lung and liver cells” (August 1, 2020- July 31, 2022; in NCE year). Role: Co-Investigator
- National Institute of Environmental Health Sciences (NIEHS). “Colorado Undergraduate Research in Environmental Health Science” (April 1, 2020- March 30, 2025). Role: Co-Program Director.
Publications and Presentations
- Bauer AK, Siegrist KJ, Wolff M, Nield L, Brüning T, Upham BL, Käfferlein HU, Plöttner S. The Carcinogenic Properties of Overlooked yet Prevalent Polycyclic Aromatic Hydrocarbons in Human Lung Epithelial Cells. Toxics. 2022 Jan 9;10(1). doi: 10.3390/toxics10010028. PubMed PMID: 35051070; PubMed Central PMCID: PMC8779510.
- Cruz-Hernandez A, Mendoza RP, Nguyen K, Harder A, Evans CM, Bauer AK, Tewari-Singh N, Brown JM. Mast Cells Promote Nitrogen Mustard-Mediated Toxicity in the Lung Associated With Proinflammatory Cytokine and Bioactive Lipid Mediator Production. Toxicol Sci. 2021 Oct 27;184(1):127-141. doi: 10.1093/toxsci/kfab107. PubMed PMID: 34453837; PubMed Central PMCID: PMC8557475.
- Siegrist KJ, Romo D, Upham BL, Armstrong M, Quinn K, Vanderlinden L, Osgood RS, Velmurugan K, Elie M, Manke J, Reinhold D, Reisdorph N, Saba L, Bauer AK. Early Mechanistic Events Induced by Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells: A Role for Eicosanoid Signaling. Toxicol Sci. 2019 May 1;169(1):180-193. doi: 10.1093/toxsci/kfz030. PubMed PMID: 30690640; PubMed Central PMCID: PMC6484882.
- Bauer AK, Umer M, Richardson VL, Cumpian AM, Harder AQ, Khosravi N, Azzegagh Z, Hara NM, Ehre C, Mohebnasab M, Caetano MS, Merrick DT, van Bokhoven A, Wistuba II, Kadara H, Dickey BF, Velmurugan K, Mann PR, Lu X, Barón AE, Evans CM, Moghaddam SJ. Requirement for MUC5AC in KRAS-dependent lung carcinogenesis. JCI Insight. 2018 Aug 9;3(15). doi: 10.1172/jci.insight.120941. eCollection 2018 Aug 9. PubMed PMID: 30089720; PubMed Central PMCID: PMC6129115.
- Cho HY, Jedlicka AE, Chang FH, Marzec J, Bauer AK, Kleeberger SR. Transcriptomics Underlying Pulmonary Ozone Pathogenesis Regulated by Inflammatory Mediators in Mice. Antioxidants (Basel). 2021 Sep 18;10(9). doi: 10.3390/antiox10091489. PubMed PMID: 34573120; PubMed Central PMCID: PMC8466999.