Research

Our Focus


Our faculty and students conduct research on population-level disease prevention, health promotion, health policy, and more. We have a tradition of excellence in research and the application of that knowledge through public health practice and service. Our experienced faculty share their research with community leaders, policymakers, and fellow researchers to better inform the public, respond to emergencies, and provide counsel on emerging health issues facing communities.

Our research- and practice-focused centers specialize in a wide range of important public health topics—including diabetes epidemiology, cancer prevention, and statistical consulting—and are nationally, if not internationally, recognized for their work. Our Center for Global Health is the only World Health Organization Collaborating Center for Promoting Family and Child Health in the Americas. We’re also home to nationally-funded research centers including the Colorado Integrated Food Safety Center of Excellence, one of six centers of its kind funded by the Centers for Disease Control & Prevention (CDC); Rocky Mountain Public Health Training Center, one of 10 centers funded by the Health Resources and Services Administration Agency; and the Center for Health, Work & Environment (one of 10 centers of its kind funded by the CDC).  

Contact Information 

If you need specific guidance on your research, contact your department chair or Associate Dean for Research, Dana Dabelea:

Our Team 

Dana Dabelea head shot

Dana Dabelea MD, PhD

Associate Dean of Research, Conrad M. Riley Distinguished Professor, Director (LEAD Center)
  • Colorado School of Public Health - Office of the Dean
  • Department of Epidemiology
  • Lifecourse Epidemiology of Adiposity & Diabetes Center

Dr. Dana Dabelea is the Conrad M. Riley Distinguished Professor of epidemiology, professor of pediatrics, and director of the Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center. For nearly 20 years, Dr. Dabelea has focused on the rising rate of type 2 diabetes in youth, and is the author of one of the first papers to highlight this trend. Originally from Romania, she trained as a physician diabetologist, completed a clinical science PhD, and then went on to spend two years of postdoctoral studies at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) where she focused on diabetes research among the Pima Indians. It was there that she became interested in the rising rates of type 2 diabetes, particularly in youth. Dr. Dabelea's research looking at diabetes during pregnancy led her to believe that a life course approach to diabetes with a specific focus on pediatric diabetes, could increase the likelihood of identifying early risk factors for the disease, as well as its progression, before chronic complications can develop.

Areas of Expertise

  • Lifecourse epidemiology
  • Pediatric obesity
  • Type 1 and type 2 diabetes
  • Diabetes prevention
  • Native American health

Education, Licensure & Certifications

  • Postdoctoral Fellowship Epidemiology, National Institutes of Health Diabetes Epidemiology and Field Studies Epidemiology, Phoenix, AZ, 1997-1999
  • PhD, Clinical Sciences, University of Medicine and Pharmacy, Timisoara, Romania, 1992-1997
  • Residency, Internal Medicine, University of Medicine and Pharmacy Timisoara, Romania, 1991-1994
  • MD, University of Medicine and Pharmacy Timisoara, Romania, 1984-1990

Resumes/CV:

Awards

  • 2017 Kelly West Award in Diabetes Epidemiology, American Diabetes Association
  • 2017 Elizabeth Gee Memorial Award, University of Colorado
  • 2014 Graduate School Mentoring Award, CU Anschutz Medical Campus
  • 2013 Conrad Riley Distinguished Professor, Colorado School of Public Health
  • 2010 Excellence in Faculty Research, Colorado School of Public Health

Affiliations

  • Chair, Scientific Planning Committee, American Diabetes Association, 2021-2023

Better Together? Learning to Align Medical, Social, and Public Health Systems to Promote Health Equity

Glen P Mays, Isabel Cuervo, Alonzo L Plough

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Public Health Impact Statement: The unfortunate constellation of rising prices, sluggish job and wage growth, and public program cutbacks makes it increasingly difficult for families to meet their basic human needs for resources like food, housing, transportation, childcare, and medical care. Over time, unmet social and economic needs transform into preventable diseases and injuries and costly medical expenditures, but public health professionals often lack the tools and resources to intervene in these issues. This issue of the American Journal of Public Health, guest edited by Glen Mays, features research studies that demonstrate the impact of system-level interventions designed to help communities align their available medical, social, and public health services in ways that optimize the use of scarce resources, close gaps in care, reduce disease and injury burden, and constrain medical spending.   

Read the Full Paper

 

 

Handling of Multicohort Data in Pooled Analysis of Environmental Exposures: Confounding by Cohort of the Relationship Between Perfluoroalkyl Substances and Birthweight in the ECHO Program

Andreas M Neophytou, Sheryl Magzamen, Brianna F Moore, Akram Alshawabkeh, Carrie V Breton, Alison E Hipwell, Kristen Lyall, John D Meeker, Thomas G O'Connor, Emily Oken, Rita Strakovsky, Dana Dabelea, For The ECHO Cohort Consortium
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Public Health Impact Statement: Multi-cohort consortia like the Environmental influences on Childhood Health Outcomes (ECHO) program allow for combined data analysis, overcoming power and generalizability limitations of smaller individual studies, though this may come at a cost of bias like cohort-level confounding. Our study shows that failure to account for this type of confounding led to bias in the relationship between prenatal PFAS exposure and birthweight with direct implications for accurate risk assessment. Various commonly used approaches to deal with this bias proved adequate in this example, though we highlight that some choice approaches may be more beneficial than others in different scenarios.


Read the Full Paper


 

BioNeuralNet: A Graph Neural Network Based Multi-Omics Network Data Analysis Tool

Vicente Ramos, Sundous Hussein, Mohamed Abdel-Hafiz, Arunangshu Sarkar, Weixuan Liu, Katerina J Kechris, Russell P Bowler, Leslie Lange, Farnoush Banaei-Kashani
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Public Health Impact Statement: Many chronic diseases result from interactions among genes, proteins, metabolites, and environmental factors. BioNeuralNet is a new method that provides a framework for integrating these diverse ("multi-omics") datasets into biologically meaningful networks that can reveal disease mechanisms that traditional approaches may miss. The software uses machine learning methods to learn patterns from complex biological networks, producing low-dimensional representations that can be used for prediction, classification, and biomarker discovery. The resulting biomarkers can be used for precision public health to identify individuals at highest risk for disease and biological subtypes that respond differently to interventions.

Read the Full Paper

Faculty Highlight of the Month

Rebecca Conway

Rebecca Conway, PhD, MPH, MA

 

Dr. Conway is an associate professor in the Department of Epidemiology at the Colorado School of Public Health. She is a diabetes epidemiologist with a broad research interest in diabetes incidence and complications. Her research interests include both type 1 and type 2 diabetes. Within diabetes, specific areas of interest include adiposity/obesity, iron as a risk factor for diabetes complications, cancer as a consequence of diabetes, and electronic health records for diabetes surveillance.

 

| Check Out Dr. Conway's Recent Publication:

"Association between Social Vulnerability Index and Rates of Carbapenem-Resistant Enterobacterales Infections in the Denver Metropolitan Region, 2016–2019"

Quick Facts


$55M in external funding

800+ publications

Featured Projects

Principal Investigator: Dana Dabelea, MD, PhD 

Researchers Involved: Dana Dabelea, Anne Starling, Brianna Moore

About the Study: Similar to the Healthy Start study, this study is apart of the Environmental Influences on Child Health Outcomes (ECHO) Study. Mile-High ECHO is a new cohort recruiting pregnant individuals and their partners, to study how exposures before and after birth affect child health outcomes. This research can be used to promote policy and practice that is aimed at reducing adverse environmental exposures. Our site works with Denver Health and the University of Colorado Hospital to enroll a diverse group of participants. As part of the nationwide ECHO consortium, we will explore how early-life exposures impact the risk of obesity and neurodevelopment. Our goal is to identify ways to improve child health from preconception through early life. 

Learn more at https://echochildren.org/ and https://www.milehighecho.org/.

Principal Investigator: Lee Newman, MD, MA

Researchers Involved: Lee Newman, Lyndsay Krisher

About the Study: Women who live in agricultural communities in Latin America are exposed to extreme heat, humidity, and air pollutants, especially if they are employed in agriculture. The goal of this 5-year NIH-supported study is to examine the environmental determinants of kidney injury among Guatemalan women working in sugarcane and banana plantations.

Recent News: Heat is a “Health Hazard Multiplier” for Sugarcane Workers in Guatemala and Others Around the World, ColoradoSPH Researchers Show

Principal Investigator: Katerina Kechris, PhD 

Researchers Involved: Katerina Kechris, Wei Perng, Leslie Lange, Ivana Yang

About the Study: In 2024, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK funded the DEFINE-T2D consortium to better understand heterogeneity in T2D. Leveraging data on clinical, genetics, omics, environmental exposures, lifestyle behaviors, and social factors, major goals of DEFINE-T2D are to: 1) develop a broadly applicable framework for identifying subtypes of T2D; and 2) increase understanding of the physiologic drivers of T2D subtypes to guide development of more effective precision interventions DEFINE-T2D is composed of four study sites (12 PIs/MPIs) bringing data from 13 cohorts, four randomized controlled trials, and six electronic health records/biobanks, contributing N>4.8 million individuals – primarily adults – with prediabetes or T2D. Data analysis coordination and operations are overseen by the Biostatistics Research Center (BRC).

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