Quick facts
Program location: CU Anschutz
Credit hours: 68
Est. time to complete: 5-7 years
In this program, you'll gain
advanced skills in analytical methods, biostatistics, and field research methods. In addition, you’ll learn about grant writing and research ethics and have the opportunity to select a
minor course of study. Our department has a strong base of funded research projects providing students with many opportunities for research support and data for dissertation projects. Our faculty are studying everything from food safety, to
diabetes, to gene-environment interactions, which means you can find the mentor
who’s right for you. We also have institutional training grant opportunities with our CHAMP T32 program for those interested in high dimensional data handling and analysis
When you leave this program, you’ll be able to rigorously investigate the genetic, behavioral, environmental, and physiological factors that underlie complex human diseases and effective preventive measures.
Quick facts
Program location: CU Anschutz
Credit hours: 68
Est. time to complete: 5-7 years
Sample careers
Staff scientist
Principal investigator
Instructor
& more
Skills you'll gain
Grant writing
Study design
Data analysis and interpretation
& more
In this program, you’ll take courses in epidemiology, biostatistics, research methods, analytical methods, and research ethics. You'll also complete a dissertation based on work completed under the supervision of one of our world-class researchers.
| Course requirement | Course ID | Credits |
| Advanced Epidemiology 1 | EPID 7631 | 3 |
| Advanced Epidemiology 2 | EPID 7632 | 3 |
| 6 |
Course requirement | Course ID | Credits |
|---|---|---|
Biostatistics Methods I | BIOS 6611 | 3 |
| Biostatistics Methods II | BIOS 6612 | 3 |
| 6 |
Course requirement | Course ID | Credits |
|---|---|---|
Research Methods with Secondary Datasets Sources | EPID 7605 | 3 |
| Epidemiologic Field Methods | EPID 7911 | 3 |
| Developing a Research Grant | EPID 7912 | 3 |
| Analytical Methods in Epidemiology * | 4 | |
| 13 |
*A minimum of 4 credits of advanced analytic coursework in biostatistics or epidemiologic methods from the ColoradoSPH
| Course requirement | Course ID | Credits |
| Advanced Communication Skills for Public Health Impact | EHOH 7405 | 3 |
Ethics and Responsible Conduct of Research OR PUBH 6655 Public Health Ethics | CLSC 7150
PUBH 6655 | 1
1 |
| Electives | 9 | |
| 13 |
Course requirement | Course ID | Credits |
|---|---|---|
Doctoral Thesis | EPID 8990 | 30 |
| Identifier | Competencies | Course Where Competency is Addressed/Assessed |
| PHD-EPID 1 | Transform scientific questions into study aims with testable hypotheses, a research protocol with appropriate data collection methods and an analysis plan. | EPID 7632 EPID 7605 EPID 7912 |
| PHD-EPID 2 | Synthesize a body of evidence, while critically evaluating methodologic quality of individual studies to identify areas of need for future investigation. | EPID 7632 EPID 7912 |
| PHD-EPID 3 | Create research proposals to answer a research or public health question using a variety of data sources; considering limitations, study design and analytic solutions. | EPID 7632 EPID 7605 EPID 7912 |
| PHD-EPID 4 | Develop statistical models appropriate to specific study designs, distinguishing between predictive, associative, and causality-based analytic approaches. | EPID 7632 |
| PHD-EPID 5 | Demonstrate mastery of a substantive area of research including knowledge and application of that knowledge in conducting original research. | EPID 7912 |
| PHD-EPID 6 | Demonstrate excellent written and oral communication skills to translate the results of research findings to the public or other professionals. | EHOH 7405 |
The next generation of biostatisticians and epidemiologists will routinely be considering complex biomarker data. Examples include multiplex cytokine data, microbiome data, -omics and require analyses of high-dimensional, often correlated data, where the interest is in describing pathways or communities, and their influence on health. Many of these datasets will be collected in longitudinal studies as well, adding to the analytic challenge and requiring advanced training in analytical methods for describing systems rather than single exposures. These complex exposures are often best examined using tools developed in fields such as quantitative community ecology and computational biology, which are outside the realm of traditional epidemiologic and biostatistical training.
This cross-disciplinary training program will teach trainees the tools for handling high-dimensional exposures and outcomes including ordination methods, clustering techniques, graph-theoretic approaches, data reduction strategies and network analysis. A focus on data visualization techniques and data communication will position trainees to both analyze increasingly ubiquitous biomarker data and effectively communicate inferences to collaborators, funders and the public. Trainees will also gain skills in reproducible research to ensure rigor and transparency. Training supported by the National Institute Of General Medical Sciences of the National Institutes of Health under Award Number T32GM165263.
Funding will start in September 2026. Funding is for up to 3 years, given sufficient progress and meeting of expectations.
For the AY26-27 year, there will be 3 pre-doctoral slots. Pre-Doctoral Fellowships are open to current or prospective PhD students in the Epidemiology and Biostatistics Departments interested in pursuing high dimensional data management, analysis and communication skills. No single criterion will be considered a hard threshold for admittance into the training program. However, given the quantitative rigor of the program, students, through either prior undergraduate coursework or a supplementary course plan to be completed prior to entry into the training program, should meet the following eligibility criteria:
Awardees are expected to devote approximately 90% of their time to research and completion of the T32 program during the first year of the award. This level of research and training time may gradually decrease over the three-year award period as the trainee progresses through the program and assumes increasing responsibilities under the guidance of their mentor.
Must be a US Citizen or Permanent Resident.
Competencies for the Pre-Doctoral Training Program in High dimensional data handling and analysis
*The activities described below represent the planned program structure; specific components and implementation details are still being developed.
| Skills/Competencies Developed | Course work | Timing |
Apply statistical concepts of basic study designs including bias, confounding and efficiency, and identify strengths and weaknesses of experimental and observational designs. Carry out exploratory and descriptive analyses of complex data using standard statistical software and methods of data summary and visualization. | BIOS 6618 (Advanced Biostatistical Methods I) | Year 1 - Year 2 |
Carry out valid and efficient modeling, estimation, model checking and inference using standard statistical methods and software. Demonstrate statistical programming proficiency, good coding style and use of reproducible research principles using leading statistical software. | BIOS 6619 (Advanced Biostatistical Methods II) | Year 1- Year 2 |
Understand complex data structures and be able to implement strategies and methods for data management, data cleaning and assessment of measurement errors and missingness. Demonstrate proficiency in tools for analyzing complete data including ordination methods, clustering methods, latent variable methods and machine learning methods. | Complex Data Analytic Methods 1* Complex Data Analytic Methods 2* High-dimensional Data elective | Year 2-4 |
| Demonstrate the ability to translate scientific evidence from high dimensional data projects and the uncertainty around results into comprehensible and culturally appropriate messages aimed at general audiences | EHOH 7405 (Advanced Communication Skills for Public Health Impact) | Year 2-3 |
| Understand the importance of reproducible research and its impact on the evidence base, implement documentation best practices for process and results of the process as well as version control. | Reproducible Research Workshop | Year 2-3 |
| Carry out independent high-dimensional data research involving implementation of complex data management, development and evaluation of novel or advanced complex data methods and their application to problems of importance in health science research, and report the methods and findings orally and in writing. | EPID 8990 or BIOS 8990 | Year 3-5 |
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Application Deadline: TBD
CU Anschutz
Fitzsimons Building
13001 East 17th Place
3rd Floor
Mail Stop B119
Aurora, CO 80045