Funding
Support from CDPHE (PI Thomas Jaenisch, Boettcher grant (PI Elena Hsieh at CHCO), CCTSI grant (PIs Brian Montague and Eric Simoes; co-investigators Thomas Jaenisch, Steven Berman, Vijaya Knight), Support from Steve Berman’s endowment.Colorado Projects
COVID-19 health care worker study
Project overview
Health Care Workers (HCW) are an essential workforce during the COVID-19 crisis. We are involved in the epidemiological aspects of a HCW study at the two big academic hospitals at Anschutz Medical Campus (AMC). The study is coordinated by a team of scientists from AMC and linked to a Biobank Protocol and an Inpatient COVID-19 protocol. Aims are to investigate prevalence and incidence of COVID-19 in HCW, stratified by job category, age, and underlying comorbidity; and to investigate the kinetics of the immune response over time.
Faculty team
Thomas Jaenisch, Molly Lamb, Stephen Berman, Brian Montague, Eric SimoesCollaborating team
The collaborating team at CHCO and UCH includes Tom Flaig, Kevin Dean, Brian Montague, Eric Simoes, Elena Hsieh, Adrie Van Bokhoven, Vijaya Knight, Thomas Jaenisch, Molly Lamb, and Stephen BermanCOVID-19 seroprevalence surveys
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Project overview
The team at CGH is involved in the design as well as operational aspects of seroprevalence surveys in collaboration with the Arapahoe County Sherriff’s office and the Tri-County Health department. In a first phase, ~500 first responders are going to be tested for COVID-19 antibodies, using both a standard ELISA (Anschutz in-house test) and an experimental multiplex assay developed by Rosemary Rochford and her team in Immunology. In a second phase, the team will apply a two-stage cluster sampling design across Arapahoe County in order to conduct the seroprevalence survey on a random sub-sample of the population. In both cases (first responder as well as general population) the first round of sampling is planned for July/August and a second round for October/November, depending on the evolution of the epidemic.
Funding
CARES Act grant awarded to the Arapahoe County Sheriff's officeFaculty team
Molly Lamb, Olivia Pluss, and Thomas JaenischCollaborating team
Lisa Miller, Jill Norris (Epidemiology), Rosemary Rochford, Katherine Basourine (Immunology), and Daniel Larremore (CU Boulder)COVID-19 seroprevalence mapping in Colorado
Project overview
The multitude of seroprevalence surveys conducted in different target populations and using different test systems asks for a harmonization in order to evaluate and display the results on a common platform. The aim of this project is to collect data from seroprevalence surveys all over Colorado and display the data on a common (map) platform, including dynamic updates over time.
Faculty team
Thomas Jaenisch, Molly Lamb, May Chu, Olivia Pluss, June Homdayjanakul