Dr. Crume is a lifecourse epidemiologist with a research focus on the functional consequences of in-utero and early life exposures during sensitive or critical periods of human development. Her research encompasses a variety of longitudinal studies of complex chronic diseases with multifactorial etiologies such as cardiovascular, metabolic disease, and congenital heart disease. She also has expertise in the design of novel surveillance systems for complex chronic diseases. Her surveillance work utilizes advanced case-finding techniques; identify reconciliation algorithms, case validation studies, and advanced analytic methods to evaluate biases present in surveillance cohorts. Her expertise in the science of population-level surveillance is supported by a decade of experience as an applied epidemiologist at the state and federal levels. Fueled by a passion for helping women with substance use issues, she designed and obtained funding to conduct research and implement impact studies on prenatal cannabis and tobacco use.