SEARCH for Diabetes in Youth (Dana Dabelea, PI; Hamman, Co-Investigator): This is a registry project aimed at identifying trends in diabetes incidence and complications in six U.S. geographic areas.
Environmental Influences on Child Health Outcomes (ECHO) / Healthy Start 3 (Dana Dabelea, PI, Hamman, Co-investigator): An NIH-wide program to combine observational data on over 80 existing cohorts in the US from birth to age 21. Healthy Start is the local cohort in this effort to explore the influence of environmental exposures on a range of outcomes including obesity, asthma, neurocognition, and positive health.
Arsenic exposure and kidney disease in the San Luis Valley, CO (Kathy James, PI, Hamman, Co-investigator
Arsenic exposure and birth outcomes in the San Luis Valley, CO (Kathy James, PI, Hamman, Co-investigator): These two studies use an historical database built by Dr. James of arsenic in ground water in the SLV as a surrogate of arsenic and other heavy metal exposures. Urine samples have also been assayed for arsenic and other heavy metals. This is linked to data from the SLV Diabetes Study to assess kidney disease, and to Colorado birth certificates and special needs registry data at the Health Department to explore birth outcomes.
The Community Activation for Prevention Study (CAPS) (Jill Litt, PI, Hamman, Co-investigator): A randomized trial of community gardening in Denver aimed at reducing risk factors for cancer and cardiometabolic diseases.
Publications and Presentations
Reynolds K, Saydah SH, Isom S, Divers J, Lawrence JM, Dabelea D, Mayer-Davis EJ, Imperatore G, Bell RA, Hamman RF. Mortality in youth-onset type 1 and type 2 diabetes: The SEARCH for Diabetes in Youth study. J Diabetes Complications. 2018 Jun;32(6):545-549 PMID: 29685480
Dabelea D, Stafford JM, Mayer-Davis EJ, D’Agostino Jr., R, Dolan L, Imperatore G, Linder G, Lawrence JM, Marcovina SM, Mottl AK, Black MH, Pop-Busui R, Saydah S, Hamman RF, Pihoker C, for the SEARCH for Diabetes in Youth Research Group. Association of type 1 diabetes vs. type 2 diabetes diagnosed during childhood and adolescence with complications during teenage years and young adulthood, JAMA, 2017;317(8):825-835.
Dabelea D, Hamman RF, Knowler WC. Chapter: Diabetes in Youth, Diabetes in America, NIDDK, 2018.https://www.niddk.nih.gov/about-niddk/strategic-plans-reports/diabetes-in-america-3rd-edition
Perreault L, Pan Q, Mather KJ, Watson KE, Hamman RF, Kahn SE: Effect of regression from prediabetes to normal glucose regulation on long-term reduction in diabetes risk: results from the Diabetes Prevention Program Outcomes Study. Lancet 379:2243-2251, 2012 PMID: 22683134
Hamman RF, Horton E, Barrett-Connor E, Bray GA, Christophi C, Crandall J, Florez J, Fowler S, Goldberg R, Kahn SE, Knowler WC, Lachin J, Murphy MB, Venditti E for the DPPOS Research Group. Factors Affecting the Decline in Incidence of Diabetes in the Diabetes Prevention Program Outcome Study (DPPOS). Diabetes. 2014;64(3):989-998 PMC4338587
Hamman RF, Bell RA, Dabelea D, D’Agostino, Jr RB, Dolan L,Imperatore G, Lawrence JM, Linder B, Marcovina SM, Mayer-Davis EJ, Pihoker C, Rodriguez BL, Saydah S, for the SEARCH for Diabetes in Youth Study Group. The SEARCH for Diabetes in Youth Study: Rationale, Findings, and Future Directions. Diab Care 37(12):3336-3344, 2014
Crume TL, Ogden L, Maligie M, Sheffield S, Bischoff KJ, McDuffie R, Daniels S, Hamman RF, Norris JM, Dabelea D: Long-term impact of neonatal breastfeeding on childhood adiposity and fat distribution among children exposed to diabetes in utero. Diab Care 34:641-645, 2011 PMID:21357361
Crume TL, Ogden L, Daniels S, Hamman RF, Norris JM, Dabelea D: The Impact of In Utero Exposure to Diabetes on Childhood Body Mass Index Growth Trajectories: The EPOCH Study. J Pediatr 158:941-946, 2011 PMID: 21238981
Diabetes Prevention Program Research Group, Knowler WC, Hamman RF, Christophi CA, Hoffman HJ, Brenneman AT, Brown-Friday JO, Goldberg R, Venditti E, Nathan DM: 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. The Lancet 374(9702):1677-1686, 2009 PMC 3135022
Dabelea D, Hamman RF Prevention of Type 2 Diabetes Mellitus. Chapter 6: In The Evidence Base for Diabetes Care. Ed. 2, Herman W, Klinmouth, A-L, Wareham N, Williams R Eds. London, John Wiley and Sons, 2010
Lawrence JM, Mayer-Davis EJ, Reynolds K, Beyer J, Pettitt DJ, D'Agostino RB, Jr., Marcovina SM, Imperatore G, Hamman RF: Diabetes in Hispanic American youth: prevalence, incidence, demographics, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diab Care 32 Suppl 2:S123-S132, 2009
Dabelea D, DeGroat J, Sorrelman C, Glass M, Percy CA, Avery C, Hu D, D'Agostino RB, Jr., Beyer J, Imperatore G, Testaverde L, Klingensmith G, Hamman RF: Diabetes in Navajo youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study. Diab Care 32 Suppl 2:S141-S147, 2009
Dabelea D, Mayer-Davis EJ, Lamichhane AP, D'Agostino RB, Jr., Liese AD, Vehik KS, Venkat Narayan KM, Zeitler P, Hamman RF: Association of Intrauterine Exposure to Maternal Diabetes and Obesity with Type 2 Diabetes in Youth: The SEARCH Case-Control Study. Diab Care 31(7): 1422-1426, 2008
The Writing Group for the SEARCH for Diabetes in Youth Study Group: Incidence of Diabetes in Youth in the United States. JAMA 297:2716-2724, 2007
Vehik K, Hamman RF, Lezotte D, Norris JM, Klingensmith G, Bloch C, Rewers M, Dabelea D: Increasing Incidence of Type 1 Diabetes in 0- to 17-Year-Old Colorado Youth. Diabetes Care 2007 Mar;30(3):503-9
Hamman RF, Wing RR, Edelstein SL, Lachin JM, Bray GA, Delahanty L, Hoskin M, Kriska AM Mayer-Davis EJ, Pi-Sunyer X, Regensteiner J, Venditti B, Wylie-RosettJ: Effect of Weight Loss with Lifestyle Intervention on Risk of Diabetes. Diabetes Care 29:2102-2107, 2006
The Look AHEAD Research Group: Look AHEAD (Action for Health in Diabetes): Design and methods for a clinical trial of weight loss for the prevention of cardiovascular disease in type 2 diabetes. Cont Clin Trials 24:610-628, 2003
Diabetes Prevention Program Research Group: Reduction in the Incidence of Type 2 diabetes with Lifestyle Intervention or Metformin. New England Journal of Medicine 346:393-403, 2002
Hamman, R.F., Baxter, J., Mulgrew, C.L., Shetterly, S.M., Swenson, C., Morgenstern, N.E. Methods and Prevalence of ADL Limitations in Hispanic and Non-Hispanic White Subjects in Rural Colorado: The San Luis Valley Health and Aging Study. Annals of Epidemlology 1999;9:225-235.
Edelstein, S.L., Knowler, W.C., Bain, R.P., Andres, R., Barrett-Connor, E.L., Dowse, G.K., Haffner, S.M., Pettitt, D.J., Sorkin, J,D, Muller, D.C., Collins, V.R., Hamman, R.F. Predictors of Progression from Impaired Glucose Tolerance to Non-Insulin Dependent Diabetes Mellitus: An Analysis of Six Prospective Studies. Diabetes 1997;46:701-710.
Marshall, J.A., Hoag, S., Shetterly, S.M., Hamman, R.F. Dietary Fat Predicts Conversion from Impaired GIucose Tolerance to NIDDM. The San Luis Valley Diabetes Study. Diabetes Care 1994; 17(1):50-56.
Hamman, R.F., Gay, E.C., Cruickshanks, K.J., Cook, M., Lezotte, D.C., Klingensmith, G.J., Chase, H.P. Colorado IDDM Registry: Incidence and Validation of IDDM in Children Aged 0-17 Yrs. Diabetes Care 1990;13(5):499-506.
Hamman, R.F., Mayer, E.J., Moo-Young, G., Hildebrandt, W., et al. Prevalence and Risk Factors of Diabetic Retinopathy Anglos and Hispanic Persons with NIDDM. The San Luis Valley Diabetes Study. Diabetes 1989;38(l0):1231-1237.
Hamman, R.F., Marshall, J.A., Baxter, J., Kahn, L.R., Mayer, E.J., Orleans, M., Murphy, J.R., Lezotte, D.C. Methods and Prevalence of Non-Insulin Dependent Diabetes Mellitus in a Biethnic Colorado Population. The San Luis Valley Diabetes Study. Amer. J Epidemiol, 1989;129:295-311.